In Silico Hemodynamics and Filtering Evaluation of a Commercial Embolic Protection Device
Ann Biomed Eng . 2021 Sep;49(9):2659-2670. doi: 10.1007/s10439-021-02846-4. Epub 2021 Aug 17.
Fecha de la publicación: 17/08/2021
Autor: Antonio Gil (1), Pedro Quintero (2), Andrea Mares (1), Juan Ribera de Serra (3), Manuel Ignacio Sánchez-Nevárez (4), Manuel Miralles (4)
Palabras clave: Computational fluid dynamics, Discrete element method, Embolic protection device, Filtration efficiency, Hemodynamics
PMID
- PMID: 34405319
- DOI: 10.1007/s10439-021-02846-4
Affiliations
1CMT-Motores Térmicos, Universitat Politècnica de València, Camino de Vera, s/n, 46022, Valencia, Spain.
2CMT-Motores Térmicos, Universitat Politècnica de València, Camino de Vera, s/n, 46022, Valencia, Spain. pedquiig@mot.upv.es.
3Instituto de Restauración del Patrimonio, Universitat Politècnica de València, Camino de Vera, s/n, 46022, Valencia, Spain.
4Servicio de Angiología y Cirugía Vascular, Hospital Universitario La Fe, Avinguda de Fernando Abril Martorell, 106, 46026, Valencia, Spain.
Abstract
During the last years, several kinds of Embolic Protection Devices (EPD) have been developed, with the aim of minimizing complication caused by thrombi generated during Carotid Artery Stenting (CAS). These devices are capable of capturing small particles generated during the intervention, avoiding cerebral stroke and improving the outcomes of the surgery. However, they have associated complications, like the increase on flow resistance associated by their use or the lack of knowledge on their actual filtration efficiency for thrombi of low size. Current work proposes a validated computational methodology in order to predict the hemodynamic features and filtering efficiency of a commercial EPD. It will be observed how Computational Fluid Dynamics predicts pressure drop with fair agreement with the experimental measurements. Finally, this work analyzes the filtration efficiency and the influence of the distribution of injected particles on this parameter. The capabilities of the filter for retaining particles of diameter below the pore size is, additionally, discussed.